Chinese goldthread (Coptis chinensis Franch., 2n = 2x=18) has been a traditional Chinese medicinal plant for thousands of years and is also named “Huanglian” in China (Li et al. 2000, Franzblau and Cross 1986, Meng et al. 2019). The alkaloids in the rhizomes of C. chinensis mainly include berberine, coptisine, jatrorrhizine, palmatine, columbamine, epiberberine, and magnoflorine (Doh et al. 2014, Yang et al. 2017, Wang et al. 2004). In medicine, the important pharmacological properties of these alkaloids are often exploited to treat infectious and inflammatory diseases and are used for the prevention and treatment of health-related issues such as cardiovascular disease, diabetes, and cancer (Meng et al. 2019, Qian et al. 2011, Meng et al. 2016, Zhen et al. 2011, Chou et al. 2017). Eudicots are the largest group of angiosperms, accounting for ~75% of all living angiosperms (Zeng et al. 2014, Ren et al. 2018, Society 2016). C. chinensis is a member of Ranunculaceae in the order Ranunculales and, together with other members of Ranunculaceae, represents an important lineage of early eudicots (Akz and Nordborg 2019, Liu et al. 2021, Zeng et al. 2014).
Previous studies support that Ranunculales diverged from all other eudicots first, followed by Proteales, and then Trochodendrales and Buxales, which are successive sister lineages to the core eudicots (APG 1998, Soltis et al. 1997, Zhen et al. 2011, Chase et al. 1993). Deciphering the ancient evolutionary events of C. chinensis is crucial for understanding the diversification of early eudicots.
News |
|
Dotplot
specie_tree
Genomic fractionation
Gene families
Syntenic gene pairs
Blast visualization
Yan Zhang
a,1, Weina Ge
a,1, Jia Teng
a,1, Yanmei Yang
a,b,1, Jianyu Wang
a,1, Zijian Yu
a, Jiaqi Wang
a, Qimeng Xiao
a, Junxin Zhao
a, Shaoqi Shen
a, Yishan Feng
a, Shoutong Bao
a, Yu Li
a, Yuxian Li
a, Tianyu Lei
a, Yuxin Pan
a, Lan Zhang
a,*, Jinpeng Wang
a,c,d,*,
Allotetraploidization event of Coptis chinensis shared by all Ranunculales.
Horticultural Plant Journal