Chinese goldthread (Coptis chinensis Franch., 2n = 2x=18) has been a traditional Chinese medicinal plant for thousands of years and is also named “Huanglian” in China (Li et al. 2000, Franzblau and Cross 1986, Meng et al. 2019). The alkaloids in the rhizomes of C. chinensis mainly include berberine, coptisine, jatrorrhizine, palmatine, columbamine, epiberberine, and magnoflorine (Doh et al. 2014, Yang et al. 2017, Wang et al. 2004). In medicine, the important pharmacological properties of these alkaloids are often exploited to treat infectious and inflammatory diseases and are used for the prevention and treatment of health-related issues such as cardiovascular disease, diabetes, and cancer (Meng et al. 2019, Qian et al. 2011, Meng et al. 2016, Zhen et al. 2011, Chou et al. 2017). Eudicots are the largest group of angiosperms, accounting for ~75% of all living angiosperms (Zeng et al. 2014, Ren et al. 2018, Society 2016). C. chinensis is a member of Ranunculaceae in the order Ranunculales and, together with other members of Ranunculaceae, represents an important lineage of early eudicots (Akz and Nordborg 2019, Liu et al. 2021, Zeng et al. 2014). Previous studies support that Ranunculales diverged from all other eudicots first, followed by Proteales, and then Trochodendrales and Buxales, which are successive sister lineages to the core eudicots (APG 1998, Soltis et al. 1997, Zhen et al. 2011, Chase et al. 1993). Deciphering the ancient evolutionary events of C. chinensis is crucial for understanding the diversification of early eudicots.
News
  • Nov. 6, 2021   The "Blast visualization", which can search function annotation and position, is now available

  • Dec. 27, 2020   The "Circle" has been updated

  • Aug. 5, 2020   The "Gene families", which can search gene of Triticeae by well-stueied gene of rice, maize, and Arabidopsis, is now available

  • May. 7, 2020   The "P-index", which can show collinearity in macro-region, is now available

  • Apr. 15, 2020   The "specie_tree", which can show collinearity in micro-region, is now available

  • Nov. 6, 2020   The "Dotplot", which can search function annotation and position, is now available

  • Aug. 2, 2019   Comparative genomics research platform of early eudicots (CGRPOEE) plantform is now open

Dotplot

Homologues

specie_tree

GeneDescription

Genomic fractionation

GOEnrichment

Gene families

GenePair

Syntenic gene pairs

MacroCollinearity

Blast visualization

MicroCollinearity
If use TGT in pulication, please cite:
Yan Zhanga,1, Weina Gea,1, Jia Tenga,1, Yanmei Yanga,b,1, Jianyu Wanga,1, Zijian Yua, Jiaqi Wanga, Qimeng Xiaoa, Junxin Zhaoa, Shaoqi Shena, Yishan Fenga, Shoutong Baoa, Yu Lia, Yuxian Lia, Tianyu Leia, Yuxin Pana, Lan Zhanga,*, Jinpeng Wanga,c,d,*, Allotetraploidization event of Coptis chinensis shared by all Ranunculales. Horticultural Plant Journal